First I made a basic design on Inkscape. Then I found the flattest section I could and propped the pumpkin up. After setting "home" for the laser, I set the properties and we gave it a try.
A few days later, we tried 2 more pumpkins. For the smaller one we used the rotary tool (that spins the object while lasering...great for etching glass jars or "hydroflasks")...got a wavy effect but it's cool. Then tried a green "pumpkin". Not bad results: